SCHEMBL13615366

SCHEMBL13615366

Cc1ccc(/C=C(\C#N)c2ccc(C)cc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.69
ESR2 Q92731 2/20 0.69
CYP1A2 P05177 2/20 0.56
CYP3A4 P08684 2/20 0.56
HIF1A Q16665 1/20 0.56
MAPT P10636 8/20 0.56
ALDH1A1 P00352 5/20 0.56
RAB9A P51151 3/20 0.56
MAPK1 P28482 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
NQO2 P16083 3/20 0.53
LMNA P02545 4/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
NPSR1 Q6W5P4 3/20 0.47
NPC1 O15118 2/20 0.47
KDM4E B2RXH2 2/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
HPGD P15428 2/20 0.47
PKM P14618 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30137200 1.00 ESR1 (0.69) ESR1ESR2CYP1A2CYP3A4HIF1A
SCHEMBL14116372 1.00 ESR1 (0.69) ESR1ESR2CYP1A2CYP3A4HIF1A
SCHEMBL823204 1.00 ESR1 (0.69) ESR1ESR2CYP1A2CYP3A4HIF1A
SCHEMBL246918 1.00 ESR1 (0.69) ESR1ESR2CYP1A2CYP3A4HIF1A
SCHEMBL14901028 0.94 ESR1 (0.62) ESR1ESR2CYP1A2CYP3A4HIF1A
SCHEMBL26867220 0.91 ESR1 (0.59) ESR1ESR2CYP1A2CYP3A4HIF1A
SCHEMBL4690787 0.91 ESR1 (0.59) ESR1ESR2CYP1A2CYP3A4HIF1A
SCHEMBL4690786 0.91 ESR1 (0.59) ESR1ESR2CYP1A2CYP3A4HIF1A
SCHEMBL8953182 0.91 MAPT (0.69) ESR1ESR2CYP1A2CYP3A4HIF1A
SCHEMBL8953176 0.91 MAPT (0.69) ESR1ESR2CYP1A2CYP3A4HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7615289-B2 Organic electroluminescent polymer having 9,9-di(fluorenyl)-2,7-fluorenyl unit and organic electroluminescent device manufactured using the same SK ENERGY CO., LTD. (KR) 2009-11-10 US disclosed
US-20070093643-A1 Organic electroluminescent polymer having 9,9-di(fluorenyl)-2,7-fluorenyl unit and organic electroluminescent device manufactured using the same SK CORPORATION (KR) 2007-04-26 US disclosed