SCHEMBL13615897

SCHEMBL13615897

c1ccc(-c2ccc3c4ccc(-c5ccccn5)cc4c4c5ccccc5c5ccccc5c4c3c2)nc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT5 O14744 2/20 0.47
WDR77 Q9BQA1 1/20 0.47
KDM4E B2RXH2 5/20 0.46
LMNA P02545 3/20 0.46
CCR1 P32246 3/20 0.46
CCR5 P51681 3/20 0.46
CCR8 P51685 3/20 0.46
CYP1A2 P05177 2/20 0.46
METAP1 P53582 2/20 0.46
POLB P06746 1/20 0.46
BLM P54132 1/20 0.46
HIF1A Q16665 1/20 0.46
DOHH Q9BU89 1/20 0.46
P4HTM Q9NXG6 1/20 0.46
DHODH Q02127 1/20 0.44
CYP2A6 P11509 1/20 0.43
PIK3CD O00329 1/20 0.43
PIK3CA P42336 1/20 0.43
PI4KA P42356 1/20 0.43
PIK3CG P48736 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13615744 1.00 PRMT5 (0.47) PRMT5WDR77KDM4ELMNACCR1
SCHEMBL13615929 1.00 PRMT5 (0.47) PRMT5WDR77KDM4ELMNACCR1
SCHEMBL24741395 0.96 PRMT5 (0.45) PRMT5WDR77KDM4ELMNACCR1
SCHEMBL13615855 0.96 KDM4E (0.50) PRMT5WDR77KDM4ELMNACCR1
SCHEMBL12589258 0.91 PRMT5 (0.44) PRMT5WDR77KDM4ELMNACCR1
SCHEMBL17229021 0.90 KDM4E (0.52) PRMT5WDR77KDM4ELMNACCR1
SCHEMBL13321297 0.90 KDM4E (0.52) PRMT5WDR77KDM4ELMNACCR1
SCHEMBL19497667 0.88 KDM4E (0.54) PRMT5WDR77KDM4ELMNACCR1
SCHEMBL12036533 0.87 PRMT5 (0.46) PRMT5WDR77KDM4ELMNACCR1
SCHEMBL16641362 0.84 PRMT5 (0.46) PRMT5WDR77KDM4ELMNACCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090273278-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-11-05 US disclosed
US-20090273278-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-11-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090273278-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OCIAD1, OCIAD2, ORMDL3 PRMT5 3212/4885WDR77 2087/4885KDM4E 3298/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.