SCHEMBL13615950

SCHEMBL13615950

c1ccc2c(c1)c1ccccc1c1c3cc(-c4ccncc4)ccc3c3ccccc3c21

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MKNK1 Q9BUB5 1/20 0.49
NOTUM Q6P988 1/20 0.48
PIK3CA P42336 1/20 0.47
IMPDH2 P12268 1/20 0.46
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.44
QDPR P09417 1/20 0.44
PDPK1 O15530 2/20 0.43
JAK2 O60674 1/20 0.43
ALK Q9UM73 1/20 0.43
MAP4K4 O95819 2/20 0.42
CHEK1 O14757 3/20 0.41
CDK2 P24941 2/20 0.41
CDK1 P06493 1/20 0.41
CDK4 P11802 1/20 0.41
CCNA2 P20248 1/20 0.41
CCND1 P24385 1/20 0.41
CCND3 P30281 1/20 0.41
DHODH Q02127 1/20 0.41
CDC7 O00311 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13615771 1.00 MKNK1 (0.49) MKNK1NOTUMPIK3CAIMPDH2LMNA
SCHEMBL13615921 1.00 MKNK1 (0.49) MKNK1NOTUMPIK3CAIMPDH2LMNA
SCHEMBL24741392 0.96 MKNK1 (0.46) MKNK1NOTUMPIK3CAIMPDH2LMNA
SCHEMBL13616009 0.96 NOTUM (0.56) MKNK1NOTUMPIK3CAIMPDH2LMNA
SCHEMBL13615875 0.92 MAPT (0.52) MKNK1NOTUMPIK3CAIMPDH2LMNA
SCHEMBL17426581 0.90 NOTUM (0.54) MKNK1NOTUMPIK3CAIMPDH2LMNA
SCHEMBL16641366 0.86 MKNK1 (0.50) MKNK1NOTUMPIK3CAIMPDH2LMNA
SCHEMBL17343955 0.86 MKNK1 (0.50) MKNK1NOTUMPIK3CAIMPDH2LMNA
SCHEMBL17343973 0.86 MKNK1 (0.50) MKNK1NOTUMPIK3CAIMPDH2LMNA
SCHEMBL17693379 0.84 NOTUM (0.54) MKNK1NOTUMPIK3CAIMPDH2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090273278-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-11-05 US disclosed
US-20090273278-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-11-05 US disclosed
EP-2112214-A1 Dibenzo[g,p]chrysene derivatives and organic electroluminescent device using the same Gracel Display Inc. (KR) 2009-10-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090273278-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OCIAD1, OCIAD2, ORMDL3 MKNK1 4653/4885NOTUM 74/4885PIK3CA 3332/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.