Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 18/20 | 0.78 |
| ▸ | PRKCB | P05771 | 10/20 | 0.54 |
| ▸ | PRKCA | P17252 | 5/20 | 0.52 |
| ▸ | PRKCG | P05129 | 3/20 | 0.52 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.48 |
| ▸ | CDK2 | P24941 | 3/20 | 0.48 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.48 |
| ▸ | CDK1 | P06493 | 2/20 | 0.48 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.48 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.48 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.48 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | CDK9 | P50750 | 1/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.47 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.47 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.47 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11937057 | 1.00 | GSK3B (0.78) | GSK3BPRKCBPRKCAPRKCGCCNA2 | |
| SCHEMBL11937056 | 0.89 | GSK3B (0.74) | GSK3BPRKCBPRKCAPRKCGCCNA2 | |
| SCHEMBL462891 | 0.88 | GSK3B (1.00) | GSK3BPRKCBPRKCAPRKCGCCNA2 | |
| SCHEMBL2979250 | 0.83 | GSK3B (0.78) | GSK3BPRKCBPRKCAPRKCGCCNA2 | |
| SCHEMBL13204273 | 0.83 | GSK3B (0.78) | GSK3BPRKCBPRKCAPRKCGCCNA2 | |
| SCHEMBL2986746 | 0.83 | GSK3B (0.78) | GSK3BPRKCBPRKCAPRKCGCCNA2 | |
| SCHEMBL11940755 | 0.81 | GSK3B (0.61) | GSK3BPRKCBPRKCAPRKCGCCNA2 | |
| SCHEMBL13204232 | 0.77 | GSK3B (0.67) | GSK3BPRKCBPRKCAPRKCGCCNA2 | |
| SCHEMBL4354893 | 0.75 | GSK3B (1.00) | GSK3BPRKCBPRKCAPRKCGCCNA2 | |
| SCHEMBL29541048 | 0.73 | FLT3 (0.58) | GSK3BPRKCBPRKCAPRKCGCCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090285756-A1 | 11C/18 F-LABELED INHIBITORS OF GLYCOGEN SYNTHASE KINASE-3 | KARIMI FARHAD | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090285756-A1 | 11C/18 F-LABELED INHIBITORS OF GLYCOGEN SYNTHASE KINASE-3 | GSK3B, GSK3A, GSKIP | GSK3B 1/4885PRKCB 24/4885PRKCA 38/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.