Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 20/20 | 0.59 |
| ▸ | HSP90AB1 | P08238 | 18/20 | 0.59 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.46 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1789959 | 0.92 | HSP90AA1 (0.59) | HSP90AA1HSP90AB1 | |
| SCHEMBL1789965 | 0.92 | HSP90AA1 (0.59) | HSP90AA1HSP90AB1 | |
| SCHEMBL12614054 | 0.91 | HSP90AA1 (0.56) | HSP90AA1HSP90AB1TRAP1 | |
| SCHEMBL12614057 | 0.89 | HSP90AA1 (0.57) | HSP90AA1HSP90AB1TRAP1 | |
| SCHEMBL12614031 | 0.88 | HSP90AA1 (0.64) | HSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL1787004 | 0.86 | HSP90AA1 (0.62) | HSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL1786998 | 0.86 | HSP90AA1 (0.62) | HSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL1058516 | 0.85 | HSP90AA1 (0.63) | HSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL1058520 | 0.85 | HSP90AA1 (0.63) | HSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL12613917 | 0.85 | HSP90AA1 (0.57) | HSP90AA1HSP90AB1TRAP1HSP90B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009139834-A1 | BIOACTIVE COMPOUNDS FOR TREATMENT OF CANCER AND NEURODEGENERATIVE DISEASES | PONIARD PHARMACEUTICALS, INC. (US) | 2009-11-19 | — | — | WO | disclosed |