Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15458050 | 0.84 | CYP2C19 (0.42) | ESR1ESR2TSHRCNR2CYP3A4 | |
| SCHEMBL15458049 | 0.84 | CYP2C19 (0.42) | ESR1ESR2TSHRCNR2CYP3A4 | |
| SCHEMBL15458048 | 0.84 | CYP2C19 (0.42) | ESR1ESR2TSHRCNR2CYP3A4 | |
| SCHEMBL10203337 | 0.84 | TSHR (0.39) | ESR1ESR2TSHRHCRTR2CNR2 | |
| SCHEMBL18237103 | 0.83 | ESR1 (0.55) | ESR1ESR2TSHRHPGDALDH1A1 | |
| SCHEMBL13383740 | 0.83 | TSHR (0.46) | TSHRHCRTR2CNR2ALDH1A1POLB | |
| SCHEMBL2632330 | 0.83 | TSHR (0.46) | TSHRHCRTR2CNR2ALDH1A1POLB | |
| SCHEMBL11938108 | 0.83 | TSHR (0.46) | TSHRHCRTR2CNR2ALDH1A1POLB | |
| SCHEMBL13383799 | 0.83 | TSHR (0.46) | TSHRHCRTR2CNR2ALDH1A1POLB | |
| SCHEMBL19981757 | 0.81 | TSHR (0.55) | ESR1ESR2TSHRHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7632579-B2 | Light emitting element and azole compound | FUJIFILM CORPORATION (JP) | 2009-12-15 | — | — | US | disclosed |