Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9679186 | 0.89 | MEN1 (0.39) | MEN1KMT2AHTTKDM4C | |
| SCHEMBL4444058 | 0.84 | MEN1 (0.37) | MEN1KMT2AHTTKDM4C | |
| SCHEMBL13460299 | 0.83 | MEN1 (0.36) | MEN1KMT2AHTTKDM4C | |
| SCHEMBL8973716 | 0.83 | MEN1 (0.36) | MEN1KMT2AHTTKDM4C | |
| SCHEMBL10431159 | 0.83 | MEN1 (0.36) | MEN1KMT2AHTTKDM4C | |
| SCHEMBL25289361 | 0.83 | MEN1 (0.36) | MEN1KMT2AHTTKDM4C | |
| SCHEMBL25240815 | 0.83 | MEN1 (0.36) | MEN1KMT2AHTTKDM4C | |
| SCHEMBL8741513 | 0.83 | MEN1 (0.36) | MEN1KMT2AHTTKDM4C | |
| SCHEMBL8973374 | 0.83 | MEN1 (0.36) | MEN1KMT2AHTTKDM4C | |
| SCHEMBL7430144 | 0.81 | MEN1 (0.35) | MEN1KMT2AHTTKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7615221-B2 | Compositions and methods for treating cancer | ONCOLOGIC, INC. (US) | 2009-11-10 | — | — | US | disclosed |
| CN-100386326-C | 1-hydroxymethyl imidazo [1, 2-a ] quinoxaline compound and application thereof | INST OF TOXIC PHARMACOLOGY ACA (CN) | 2008-05-07 | — | — | CN | disclosed |
| CN-1609105-A | 1-hydroxymethyl imidazo [1, 2-alpha ] quinoxaline compound and application thereof | INST OF TOXIC PHARMACOLOGY ACA (CN) | 2005-04-27 | — | — | CN | disclosed |