Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 20/20 | 0.59 |
| ▸ | HRH1 | P35367 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3082444 | 0.79 | HRH3 (0.65) | HRH3HRH1 | |
| SCHEMBL1640007 | 0.78 | HRH3 (0.58) | HRH3HRH1 | |
| SCHEMBL1640524 | 0.76 | HRH3 (0.61) | HRH3HRH1 | |
| SCHEMBL3087255 | 0.75 | HRH3 (1.00) | HRH3HRH1 | |
| SCHEMBL13404399 | 0.75 | HRH3 (0.67) | HRH3HRH1 | |
| SCHEMBL1640092 | 0.74 | HRH3 (0.53) | HRH3HRH1 | |
| SCHEMBL3091059 | 0.74 | HRH3 (1.00) | HRH3HRH1 | |
| SCHEMBL14372308 | 0.74 | HRH3 (0.78) | HRH3 | |
| SCHEMBL5159797 | 0.74 | HRH3 (0.78) | HRH3HRH1 | |
| SCHEMBL3100886 | 0.74 | HRH3 (0.70) | HRH3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009142732-A2 | SUBSTITUTED PYRIDAZINONE DERIVATIVES AS HISTAMINE-3 (H3) RECEPTOR LIGANDS | CEPHALON, INC. (US) | 2009-11-26 | — | — | WO | disclosed |