Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 16/20 | 0.62 |
| ▸ | CNR1 | P21554 | 11/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | RORA | P35398 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | RORB | Q92753 | 1/20 | 0.33 |
| ▸ | PDE1A | P54750 | 2/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.33 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2736765 | 0.84 | CNR2 (0.75) | CNR2CNR1 | |
| SCHEMBL2736761 | 0.75 | CNR2 (0.71) | CNR2CNR1 | |
| SCHEMBL2736768 | 0.70 | CNR2 (0.76) | CNR2CNR1 | |
| SCHEMBL13531312 | 0.70 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL2736590 | 0.69 | CNR2 (0.67) | CNR2CNR1 | |
| SCHEMBL5515473 | 0.68 | CNR2 (0.61) | CNR2CNR1 | |
| SCHEMBL2746153 | 0.68 | CNR2 (0.61) | CNR2CNR1 | |
| SCHEMBL14865324 | 0.67 | CNR2 (0.74) | CNR2CNR1 | |
| SCHEMBL2736764 | 0.67 | CNR2 (0.61) | CNR2CNR1 | |
| SCHEMBL2736733 | 0.65 | CNR2 (0.57) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477186-B1 | ANTIPRURITICS | SHIONOGI & CO (JP) | 2009-11-11 | — | — | EP | disclosed |