SCHEMBL13618696

SCHEMBL13618696

COc1ccc2c(c1)c(-c1ccc(C(C)C)cc1)nc(=O)n2Cc1ccc(CF)cc1

nearest known ligand 0.74

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CASR P41180 20/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3843143 0.95 CASR (0.81) CASR
SCHEMBL3842917 0.93 CASR (0.73) CASR
SCHEMBL3841886 0.93 CASR (0.75) CASR
SCHEMBL3841592 0.92 CASR (0.74) CASR
SCHEMBL3842794 0.91 CASR (0.73) CASR
SCHEMBL3843537 0.91 CASR (0.73) CASR
SCHEMBL3470576 0.91 CASR (0.76) CASR
SCHEMBL3842436 0.91 CASR (0.69) CASR
SCHEMBL3842995 0.90 CASR (0.71) CASR
SCHEMBL3841229 0.89 CASR (0.68) CASR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1401451-B1 QUINAZOLINE DERIVATIVES WHICH PROMOTE THE RELEASE OF PARATHYROID HORMONE NOVARTIS AG (CH) 2009-11-11 EP disclosed