Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 9/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13237887 | 0.86 | PDE5A (0.53) | PDE5AALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL2953485 | 0.83 | PDE5A (0.67) | PDE5AALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL7500320 | 0.83 | PDE5A (0.46) | PDE5AALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL2950333 | 0.82 | PDE5A (0.46) | PDE5AALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL5564260 | 0.80 | PDE5A (1.00) | PDE5AALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL7094721 | 0.79 | ADORA1 (0.50) | PDE5AALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL7093526 | 0.76 | KMT2A (0.50) | ALDH1A1KDM4EHPGDSMN1; SMN2LMNA | |
| SCHEMBL5103308 | 0.74 | PDE5A (0.48) | PDE5AALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL7094701 | 0.73 | ESR1 (0.53) | PDE5AALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL7096390 | 0.73 | BTK (0.42) | PDE5AALDH1A1KDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1425011-B1 | ENHANCEMENT OF LEARNING AND MEMORY AND TREATMENT OF AMNESIA | CARLSBAD TECHNOLOGY INC (US) | 2009-11-04 | — | — | EP | disclosed |