Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2146983 | 1.00 | CHRM2 (0.49) | CHRM2CHRM1CHRM3CYP1A2POLB | |
| SCHEMBL16040748 | 1.00 | CHRM2 (0.49) | CHRM2CHRM1CHRM3CYP1A2POLB | |
| SCHEMBL8383028 | 1.00 | CHRM2 (0.49) | CHRM2CHRM1CHRM3CYP1A2POLB | |
| SCHEMBL6347851 | 1.00 | CHRM2 (0.49) | CHRM2CHRM1CHRM3CYP1A2POLB | |
| SCHEMBL6347848 | 1.00 | CHRM2 (0.49) | CHRM2CHRM1CHRM3CYP1A2POLB | |
| SCHEMBL26039903 | 0.88 | CHRM2 (0.46) | CHRM2CHRM1CHRM3NR1H2HSD17B10 | |
| SCHEMBL19477755 | 0.87 | CHRM2 (0.45) | CHRM2CHRM1CHRM3CYP1A2POLB | |
| SCHEMBL8274294 | 0.86 | NR1H2 (0.41) | CHRM2CHRM1CHRM3CYP1A2POLB | |
| SCHEMBL20713877 | 0.86 | CHRM2 (0.47) | CHRM2CHRM1CHRM3CYP1A2POLB | |
| SCHEMBL19865492 | 0.86 | CHRM2 (0.47) | CHRM2CHRM1CHRM3CYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009141091-A1 | NOVEL [F-18] -LABELLED L-GLUTAMIC ACID- AND L-GLUTAMINE DERIVATIVES (I), USE THEREOF AND METHOD FOR THEIR PRODUCTION | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-11-26 | — | — | WO | disclosed |