SCHEMBL13619025

SCHEMBL13619025

CC(C)(C)OC(=O)N1Cc2ccc(C(=O)N[C@@H]3CCCC[C@@H]3NC(=O)c3cc4cc(Cl)ccc4[nH]3)cc2C1

nearest known ligand 0.55

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
F10 P00742 15/20 0.55
F2 P00734 4/20 0.50
EHMT2 Q96KQ7 1/20 0.47
SMYD3 Q9H7B4 1/20 0.45
PYGL P06737 3/20 0.44
PYGM P11217 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4093550 0.84 F10 (0.54) F10F2EHMT2
SCHEMBL4083313 0.84 F10 (0.54) F10F2EHMT2
SCHEMBL4095864 0.82 SMYD3 (0.54) F10F2EHMT2SMYD3PYGL
SCHEMBL4083426 0.82 SMYD3 (0.54) F10F2EHMT2SMYD3PYGL
SCHEMBL3338579 0.82 SMYD3 (0.54) F10F2EHMT2SMYD3PYGL
SCHEMBL4095868 0.82 SMYD3 (0.54) F10F2EHMT2SMYD3PYGL
SCHEMBL3335060 0.82 SMYD3 (0.54) F10F2EHMT2SMYD3PYGL
SCHEMBL3335058 0.82 SMYD3 (0.54) F10F2EHMT2SMYD3PYGL
SCHEMBL4083427 0.82 SMYD3 (0.54) F10F2EHMT2SMYD3PYGL
SCHEMBL4089163 0.82 F10 (0.72) F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090281074-A1 DRUG COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING THROMBOSIS OR EMBOLISM DAIICHI PHARMACEUTICAL CO., LTD (JP) 2009-11-12 US disclosed
US-20090281074-A1 DRUG COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING THROMBOSIS OR EMBOLISM DAIICHI PHARMACEUTICAL CO., LTD (JP) 2009-11-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090281074-A1 DRUG COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING THROMBOSIS OR EMBOLISM C1R, C9, F2 F10 127/4885F2 3/4885EHMT2 4698/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.