Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 20/20 | 0.77 |
| ▸ | GIPR | P48546 | 12/20 | 0.68 |
| ▸ | VIPR2 | P41587 | 4/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.68 |
| ▸ | VIPR1 | P32241 | 1/20 | 0.68 |
| ▸ | DUSP2 | Q05923 | 1/20 | 0.68 |
| ▸ | GLP1R | P43220 | 2/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL675778 | 0.85 | GCGR (0.86) | GCGRGIPRVIPR2CYP1A2CYP3A4 | |
| SCHEMBL12847094 | 0.84 | GCGR (0.79) | GCGRGIPRVIPR2CYP1A2CYP3A4 | |
| Mk-0893 SCHEMBL675777 | 0.81 | GCGR (1.00) | GCGRGIPRVIPR2CYP1A2CYP3A4 | |
| Mk-0893 SCHEMBL2355321 | 0.81 | GCGR (1.00) | GCGRGIPRVIPR2CYP1A2CYP3A4 | |
| Mk-0893 SCHEMBL29363684 | 0.81 | GCGR (1.00) | GCGRGIPRVIPR2CYP1A2CYP3A4 | |
| SCHEMBL2251012 | 0.80 | GCGR (0.87) | GCGRGIPRVIPR2CYP1A2CYP3A4 | |
| SCHEMBL9071632 | 0.79 | GCGR (0.84) | GCGRGIPRVIPR2CYP1A2CYP3A4 | |
| SCHEMBL9071560 | 0.78 | GCGR (0.82) | GCGRGIPRVIPR2CYP1A2CYP3A4 | |
| SCHEMBL9071080 | 0.77 | GCGR (1.00) | GCGRGIPRCYP3A4CYP2C8CYP2C9 | |
| SCHEMBL2667434 | 0.77 | GCGR (0.80) | GCGRGIPRVIPR2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140342-A1 | GLUCAGON RECEPTOR ANTAGONISTS, COMPOSITIONS, AND METHODS FOR THEIR USE | SCHERING CORPORATION (US) | 2009-11-19 | — | — | WO | disclosed |