Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | THRB | P10828 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | RECQL | P46063 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.42 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14427992 | 0.91 | MAPT (0.48) | MAPTTHRBSMN1; SMN2KDM4EPKM | |
| SCHEMBL13619826 | 0.90 | MAPT (0.48) | MAPTTHRBSMN1; SMN2KDM4EPKM | |
| SCHEMBL14427976 | 0.89 | MAPT (0.46) | MAPTTHRBSMN1; SMN2KDM4EPKM | |
| SCHEMBL14427994 | 0.88 | MAPT (0.46) | MAPTTHRBSMN1; SMN2KDM4EPKM | |
| SCHEMBL14427993 | 0.87 | MAPT (0.46) | MAPTTHRBSMN1; SMN2KDM4EPKM | |
| SCHEMBL13619894 | 0.87 | MAPT (0.46) | MAPTTHRBSMN1; SMN2KDM4EPKM | |
| SCHEMBL13619786 | 0.87 | MAPT (0.64) | MAPTTHRBSMN1; SMN2KDM4EPKM | |
| SCHEMBL13619814 | 0.87 | MAPT (0.44) | MAPTTHRBSMN1; SMN2KDM4EPKM | |
| SCHEMBL14440461 | 0.87 | MAPT (0.44) | MAPTTHRBSMN1; SMN2KDM4EPKM | |
| SCHEMBL13619792 | 0.86 | MAPT (0.43) | MAPTTHRBSMN1; SMN2KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090280060-A1 | PHOTOCHROMIC PROBES | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2009-11-12 | — | — | US | disclosed |
| US-20090280060-A1 | PHOTOCHROMIC PROBES | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2009-11-12 | — | — | US | disclosed |
| US-20070195309-A1 | PHOTOCHROMIC PROBES | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2007-08-23 | — | — | US | disclosed |
| US-20070195309-A1 | PHOTOCHROMIC PROBES | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070195309-A1 | PHOTOCHROMIC PROBES | ORAI1, TRPC1, STIM1 | MAPT 1551/4885THRB 4313/4885SMN1; SMN2 4852/4885 |
| US-20090280060-A1 | PHOTOCHROMIC PROBES | ORAI1, TRPC1, STIM1 | MAPT 1551/4885THRB 4313/4885SMN1; SMN2 4852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.