Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | GFER | P55789 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ALPG | P10696 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TLR3 | O15455 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.38 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14440467 | 0.86 | MEN1 (0.62) | MEN1KMT2AGFERGAAMAPT | |
| SCHEMBL13619865 | 0.86 | MEN1 (0.60) | MEN1KMT2AGFERGAAMAPT | |
| SCHEMBL13619867 | 0.86 | MEN1 (0.62) | MEN1KMT2AGFERGAAMAPT | |
| SCHEMBL8680569 | 0.82 | MEN1 (0.64) | MEN1KMT2AGFERGAAMAPT | |
| SCHEMBL8680328 | 0.81 | MEN1 (0.63) | MEN1KMT2AGFERGAAMAPT | |
| SCHEMBL29492998 | 0.81 | MAPT (0.70) | MEN1KMT2AGFERGAAMAPT | |
| SCHEMBL12922324 | 0.81 | MAPT (0.70) | MEN1KMT2AGFERGAAMAPT | |
| SCHEMBL79311 | 0.81 | MAPT (0.70) | MEN1KMT2AGFERGAAMAPT | |
| SCHEMBL29466131 | 0.81 | MAPT (0.70) | MEN1KMT2AGFERGAAMAPT | |
| SCHEMBL8680133 | 0.81 | MEN1 (0.80) | MEN1KMT2AGFERGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090280060-A1 | PHOTOCHROMIC PROBES | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2009-11-12 | — | — | US | disclosed |
| US-20090280060-A1 | PHOTOCHROMIC PROBES | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2009-11-12 | — | — | US | disclosed |
| US-20070195309-A1 | PHOTOCHROMIC PROBES | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2007-08-23 | — | — | US | disclosed |
| US-20070195309-A1 | PHOTOCHROMIC PROBES | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070195309-A1 | PHOTOCHROMIC PROBES | ORAI1, TRPC1, STIM1 | MEN1 2320/4885KMT2A 4480/4885GFER 1174/4885 |
| US-20090280060-A1 | PHOTOCHROMIC PROBES | ORAI1, TRPC1, STIM1 | MEN1 2320/4885KMT2A 4480/4885GFER 1174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.