Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCNN1A | P37088 | 9/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.31 |
| ▸ | PPARA | Q07869 | 2/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10125897 | 0.93 | SCNN1A (0.38) | SCNN1ASLC2A1KDM4EALDH1A1HPGD | |
| SCHEMBL708473 | 0.90 | SCNN1A (0.51) | SCNN1AKDM4EALDH1A1HPGD | |
| SCHEMBL13620861 | 0.87 | SCNN1A (0.48) | SCNN1AKDM4EKMT2A | |
| SCHEMBL10116013 | 0.84 | SCNN1A (0.48) | SCNN1AKDM4EALDH1A1HPGD | |
| SCHEMBL709519 | 0.83 | SCNN1A (0.49) | SCNN1AKDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL709294 | 0.83 | SCNN1A (0.48) | SCNN1AKDM4EALDH1A1HPGD | |
| SCHEMBL707207 | 0.82 | SCNN1A (0.46) | SCNN1ASLC2A1KDM4EALDH1A1HPGD | |
| SCHEMBL15452106 | 0.82 | SCNN1A (0.39) | SCNN1ASLC2A1KDM4EALDH1A1HPGD | |
| SCHEMBL708287 | 0.81 | SCNN1A (0.45) | SCNN1AKDM4EALDH1A1HPGD | |
| SCHEMBL16808345 | 0.80 | SCNN1A (0.45) | SCNN1ASLC2A1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009139948-A1 | POLY AROMATIC SODIUM CHANNEL BLOCKERS | JOHNSON MICHAEL R (US) | 2009-11-19 | — | — | WO | disclosed |