⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9945755 | 0.74 | — | — | |
| SCHEMBL15799954 | 0.74 | — | — | |
| SCHEMBL20845601 | 0.74 | — | — | |
| SCHEMBL10005358 | 0.71 | — | — | |
| SCHEMBL20922076 | 0.71 | — | — | |
| SCHEMBL24990247 | 0.70 | — | — | |
| SCHEMBL681245 | 0.70 | — | — | |
| SCHEMBL12027034 | 0.70 | KDM4E (0.31) | — | |
| SCHEMBL12256345 | 0.69 | — | — | |
| SCHEMBL25676742 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023051628-A1 | SOS1 INHIBITORS HAVING PYRIDO SIX-MEMBERED RING STRUCTURE | 上海海和药物研究开发股份有限公司 | 2023-04-06 | — | — | WO | disclosed |
| WO-2023003862-A1 | CXCR4 MODULATORS AND USES RELATED THERETO | EMORY UNIVERSITY (US) | 2023-01-26 | — | — | WO | disclosed |
| WO-2021213521-A1 | CBP/EP300 INHIBITOR AND USE THEREOF | 南京药石科技股份有限公司 (CN) | 2021-10-28 | — | — | WO | disclosed |
| WO-2021108683-A1 | COVALENT RAS INHIBITORS AND USES THEREOF | Revolution Medicines, Inc. (US) | 2021-06-03 | — | — | WO | disclosed |
| US-9580393-B2 | 6-substituted quinazolinone inhibitors | UNIVERSITY OF KANSAS (US) | 2017-02-28 | — | — | US | disclosed |
| EP-2701510-B1 | PYRAZOLOPYRIDAZINES AND METHODS FOR TREATING RETINAL-DEGENERATIVE DISEASES AND HEARING LOSS ASSOCIATED WITH USHER SYNDROME | USHER III INITIATIVE INC (US) | 2017-02-15 | — | — | EP | disclosed |
| WO-2014093869-A1 | 6-SUBSTITUTED QUINAZOLINONE INHIBITORS | UNIVERSITY OF KANSAS (US) | 2014-06-19 | — | — | WO | disclosed |
| US-20090281072-A1 | Diaminopyrimidinecarboxamide Derivative | ASTELLAS PHARM INC. (JP) | 2009-11-12 | — | — | US | disclosed |