Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 19/20 | 0.57 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13621914 | 0.87 | CCR1 (0.55) | CCR1CYP17A1CYP1A2 | |
| SCHEMBL1136001 | 0.86 | CCR1 (0.75) | CCR1 | |
| SCHEMBL13621675 | 0.86 | CCR1 (0.59) | CCR1 | |
| SCHEMBL13622319 | 0.82 | CCR1 (0.76) | CCR1 | |
| SCHEMBL13621925 | 0.81 | CCR1 (0.57) | CCR1 | |
| SCHEMBL13622426 | 0.80 | CCR1 (0.59) | CCR1 | |
| SCHEMBL13622100 | 0.79 | CCR1 (0.68) | CCR1 | |
| SCHEMBL13621762 | 0.79 | CCR1 (0.56) | CCR1 | |
| SCHEMBL13621765 | 0.79 | CCR1 (0.56) | CCR1 | |
| SCHEMBL13622318 | 0.78 | CCR1 (0.59) | CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009134666-A1 | INDAZOLE COMPOUNDS AS CCR1 RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-11-05 | — | — | WO | disclosed |