Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RYR2 | Q92736 | 19/20 | 0.78 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9635059 | 0.88 | RYR2 (0.72) | RYR2KCNH2NOTUM | |
| SCHEMBL6867029 | 0.88 | RYR2 (1.00) | RYR2KCNH2NOTUM | |
| SCHEMBL6866534 | 0.85 | RYR2 (0.78) | RYR2KCNH2NOTUM | |
| SCHEMBL6867212 | 0.85 | RYR2 (0.78) | RYR2KCNH2NOTUM | |
| SCHEMBL6866477 | 0.81 | RYR2 (0.72) | RYR2KCNH2NOTUM | |
| SCHEMBL7560987 | 0.81 | RYR2 (0.72) | RYR2KCNH2NOTUM | |
| SCHEMBL6866625 | 0.81 | RYR2 (1.00) | RYR2 | |
| SCHEMBL13622149 | 0.80 | RYR2 (0.71) | RYR2KCNH2 | |
| SCHEMBL807121 | 0.79 | RYR2 (0.72) | RYR2KCNH2 | |
| SCHEMBL806938 | 0.79 | RYR2 (1.00) | RYR2KCNH2NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090292119-A1 | METHODS FOR SYNTHESIZING BENZOTHIAZEPINE COMPOUNDS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2009-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090292119-A1 | METHODS FOR SYNTHESIZING BENZOTHIAZEPINE COMPOUNDS | KCNB2, KCNJ2, KCNJ5 | RYR2 275/4885KCNH2 19/4885NOTUM 336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.