Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 14/20 | 0.56 |
| ▸ | CRBN | Q96SW2 | 14/20 | 0.56 |
| ▸ | GRAMD1A | Q96CP6 | 6/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12301883 | 0.92 | DDB1 (0.68) | DDB1CRBNGRAMD1A | |
| SCHEMBL19008357 | 0.81 | DDB1 (0.66) | DDB1CRBN | |
| SCHEMBL23301680 | 0.81 | DDB1 (0.61) | DDB1CRBNGRAMD1A | |
| SCHEMBL12250730 | 0.80 | CRBN (0.75) | DDB1CRBN | |
| SCHEMBL12250744 | 0.79 | DDB1 (0.76) | DDB1CRBN | |
| SCHEMBL30009422 | 0.79 | DDB1 (0.76) | DDB1CRBN | |
| SCHEMBL12250734 | 0.79 | DDB1 (0.76) | DDB1CRBN | |
| SCHEMBL501914 | 0.79 | DDB1 (0.76) | DDB1CRBN | |
| SCHEMBL2381475 | 0.78 | DDB1 (0.74) | DDB1CRBN | |
| SCHEMBL30312787 | 0.78 | DDB1 (0.58) | DDB1CRBNGRAMD1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090286986-A1 | ISOINDOLE-IMIDE COMPOUNDS, COMPOSITIONS, AND USES THEREOF | CELGENE CORPORATION | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286986-A1 | ISOINDOLE-IMIDE COMPOUNDS, COMPOSITIONS, AND USES THEREOF | TNF, IKZF3, TNFRSF1A | DDB1 3627/4885CRBN 1695/4885GRAMD1A 4325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.