Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 14/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1362506 | 0.84 | CHRM3 (0.53) | CHRM3APAF1UBE2NCHRM2CHRM1 | |
| SCHEMBL4193656 | 0.81 | CHRM3 (0.51) | CHRM3CHRM2CHRM1 | |
| SCHEMBL3411496 | 0.81 | CHRM3 (0.40) | CHRM3CHRM2CHRM1 | |
| SCHEMBL1365235 | 0.81 | CHRM3 (0.40) | CHRM3CHRM2CHRM1 | |
| SCHEMBL1362265 | 0.78 | CHRM3 (0.48) | CHRM3CHRM2CHRM1 | |
| SCHEMBL13761063 | 0.78 | CHRM3 (0.68) | CHRM3CHRM2CHRM1 | |
| SCHEMBL1363801 | 0.77 | CHRM3 (0.53) | CHRM3APAF1UBE2NCHRM2CHRM1 | |
| SCHEMBL1630333 | 0.72 | CHRM3 (0.54) | CHRM3CHRM2CHRM1 | |
| SCHEMBL1362397 | 0.72 | ERN1 (0.47) | MEN1KMT2A | |
| SCHEMBL13761230 | 0.72 | CHRM3 (0.47) | CHRM3APAF1UBE2NCHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067408-B2 | Dual pharmacophores—PDE4-muscarinic antagonistics | GLAXO GROUP LIMITED (GB) | 2011-11-29 | — | — | US | disclosed |