Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 14/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4444404 | 0.90 | MCHR1 (0.52) | MCHR1KCNH2CYP3A4 | |
| SCHEMBL4442735 | 0.88 | MCHR1 (0.51) | MCHR1KCNH2CYP3A4 | |
| SCHEMBL2891165 | 0.73 | MCHR1 (1.00) | MCHR1KCNH2 | |
| SCHEMBL4457815 | 0.73 | MCHR1 (0.50) | MCHR1 | |
| SCHEMBL1753898 | 0.73 | MCHR1 (0.54) | MCHR1KCNH2CYP3A4 | |
| SCHEMBL1005412 | 0.72 | MCHR1 (1.00) | MCHR1CYP3A4 | |
| Hydrochloric Acid SCHEMBL1003922 | 0.72 | MCHR1 (0.98) | MCHR1CYP3A4 | |
| SCHEMBL18154549 | 0.72 | MCHR1 (0.61) | MCHR1KCNH2CYP3A4 | |
| SCHEMBL10059384 | 0.71 | MCHR1 (0.70) | MCHR1KCNH2 | |
| SCHEMBL4881868 | 0.71 | MCHR1 (0.71) | MCHR1KCNH2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009137270-A2 | AZETIDINE DERIVATIVES | H. LUNDBECK A/S (DK) | 2009-11-12 | — | — | WO | disclosed |