Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12502808 | 0.94 | NTRK1 (0.54) | NTRK1 | |
| SCHEMBL1430791 | 0.90 | NTRK1 (0.52) | NTRK1 | |
| SCHEMBL13623000 | 0.90 | NTRK1 (0.62) | NTRK1 | |
| SCHEMBL13623283 | 0.89 | NTRK1 (0.61) | NTRK1 | |
| SCHEMBL1430881 | 0.88 | NTRK1 (0.52) | NTRK1 | |
| SCHEMBL13622996 | 0.85 | NTRK1 (0.62) | NTRK1 | |
| SCHEMBL13622992 | 0.84 | NTRK1 (0.65) | NTRK1 | |
| SCHEMBL12503574 | 0.84 | NTRK1 (0.62) | NTRK1 | |
| SCHEMBL13623110 | 0.82 | NTRK1 (0.61) | NTRK1 | |
| SCHEMBL13622964 | 0.82 | NTRK1 (0.56) | NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140128-A2 | COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS | IRM LLC (BM) | 2009-11-19 | — | — | WO | disclosed |