Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL707247 | 0.87 | CA12 (0.54) | CA12CA1CA9MAP4K4CYP17A1 | |
| SCHEMBL714227 | 0.87 | CA12 (0.54) | CA12CA1CA9MAP4K4CYP17A1 | |
| SCHEMBL29425603 | 0.87 | CA12 (0.54) | CA12CA1CA9MAP4K4CYP17A1 | |
| SCHEMBL30078221 | 0.87 | CA12 (0.54) | CA12CA1CA9MAP4K4CYP17A1 | |
| SCHEMBL30887589 | 0.87 | CA1 (0.48) | CA12CA1CA9MAP4K4CYP17A1 | |
| SCHEMBL23033538 | 0.87 | CA12 (0.48) | CA12CA1CA9MAP4K4CYP17A1 | |
| SCHEMBL1094945 | 0.86 | CA12 (0.47) | CA12CA1CA9MAP4K4CYP17A1 | |
| SCHEMBL397557 | 0.86 | CA12 (0.47) | CA12CA1CA9MAP4K4CYP17A1 | |
| SCHEMBL13193090 | 0.86 | CA12 (0.47) | CA12CA1CA9MAP4K4CYP17A1 | |
| SCHEMBL16044613 | 0.86 | CA12 (0.47) | CA12CA1CA9MAP4K4CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622592-B2 | Carbonylamino-benzimidazole derivatives as androgen receptor modulators | MERCK & CO., INC. (US) | 2009-11-24 | — | — | US | disclosed |