Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 3/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.46 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.46 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.46 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | METAP1 | P53582 | 8/20 | 0.42 |
| ▸ | METAP2 | P50579 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4372898 | 0.93 | MCHR1 (0.46) | CYP2D6METAP1METAP2KDM4ENPC1 | |
| SCHEMBL4371215 | 0.92 | MEN1 (0.49) | CYP2D6METAP1METAP2KDM4ENPC1 | |
| SCHEMBL4365502 | 0.88 | METAP1 (0.49) | CYP2D6METAP1METAP2KDM4ENPC1 | |
| SCHEMBL4376324 | 0.87 | METAP1 (0.48) | CYP2D6METAP1METAP2KDM4ENPC1 | |
| SCHEMBL4380108 | 0.86 | METAP1 (0.49) | CYP2D6METAP1METAP2KDM4ENPC1 | |
| SCHEMBL4363482 | 0.86 | METAP1 (0.52) | CYP2D6METAP1METAP2KDM4ENPC1 | |
| SCHEMBL4372206 | 0.84 | METAP1 (0.45) | CYP2D6METAP1METAP2KDM4ENPC1 | |
| SCHEMBL4371202 | 0.84 | KDR (0.55) | CYP2D6METAP1METAP2KDM4ENPC1 | |
| SCHEMBL4367763 | 0.84 | KDR (0.55) | CYP2D6METAP1METAP2KDM4ENPC1 | |
| SCHEMBL4367584 | 0.83 | MAPT (0.50) | CYP2D6METAP1METAP2KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622592-B2 | Carbonylamino-benzimidazole derivatives as androgen receptor modulators | MERCK & CO., INC. (US) | 2009-11-24 | — | — | US | disclosed |