Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.48 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1952758 | 0.83 | SCN5A (0.58) | SCN5ASCN9ASCN10A | |
| Chloromethane SCHEMBL28360619 | 0.82 | SCN5A (0.47) | SCN5ASCN9ASCN10A | |
| SCHEMBL11138205 | 0.82 | SCN5A (0.33) | SCN5ASCN9ASCN10A | |
| SCHEMBL1927023 | 0.82 | SCN5A (0.49) | SCN5ASCN9ASCN10A | |
| SCHEMBL4023092 | 0.82 | SCN5A (0.49) | SCN5ASCN9ASCN10A | |
| SCHEMBL2016482 | 0.80 | SCN5A (0.48) | SCN5ASCN9ASCN10A | |
| SCHEMBL23277004 | 0.79 | SMN1; SMN2 (0.51) | SCN5ASCN9ASCN10A | |
| SCHEMBL11225641 | 0.79 | SCN5A (0.44) | SCN5ASCN9ASCN10A | |
| SCHEMBL5836784 | 0.78 | CYP1A2 (0.48) | — | |
| SCHEMBL6946542 | 0.78 | SCN5A (0.47) | SCN5ASCN9ASCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109400645-A | A kind of phosphoric acid derivatives and preparation method and purposes | 四川海思科制药有限公司 | 2019-03-01 | — | — | CN | disclosed |
| US-9023813-B2 | Synthesis and use of glycoside derivatives of propofol | NuTek Pharma Ltd. (US) | 2015-05-05 | — | — | US | disclosed |
| US-20120295866-A1 | Synthesis And Use Of Glycoside Pro-Drug Analogs | NuTek Pharma Ltd. | 2012-11-22 | — | — | US | disclosed |
| US-20120264702-A1 | Synthesis And Use Of Glycoside Derivatives of Propofol | NuTek Pharma Ltd. | 2012-10-18 | — | — | US | disclosed |
| US-8067455-B2 | Amino acid derived prodrugs of propofol, compositions, uses and crystalline forms thereof | XENOPORT, INC. (US) | 2011-11-29 | — | — | US | disclosed |
| US-8067455-B2 | Amino acid derived prodrugs of propofol, compositions, uses and crystalline forms thereof | XENOPORT, INC. (US) | 2011-11-29 | — | — | US | disclosed |
| US-8067455-B2 | Amino acid derived prodrugs of propofol, compositions, uses and crystalline forms thereof | XENOPORT, INC. (US) | 2011-11-29 | — | — | US | disclosed |
| US-20100087536-A1 | AMINO ACID DERIVED PRODRUGS OF PROPOFOL, COMPOSITIONS, USES AND CRYSTALLINE FORMS THEREOF | XENOPORT, INC. (US) | 2010-04-08 | — | — | US | disclosed |
| US-20100087536-A1 | AMINO ACID DERIVED PRODRUGS OF PROPOFOL, COMPOSITIONS, USES AND CRYSTALLINE FORMS THEREOF | XENOPORT, INC. (US) | 2010-04-08 | — | — | US | disclosed |
| US-20100087536-A1 | AMINO ACID DERIVED PRODRUGS OF PROPOFOL, COMPOSITIONS, USES AND CRYSTALLINE FORMS THEREOF | XENOPORT, INC. (US) | 2010-04-08 | — | — | US | disclosed |
| US-5981595-A | LOWERS BLOOD CHOLESTEROL LEVELS | WARNER-LAMBERT COMPANY (US) | 1999-11-09 | — | — | US | disclosed |
| US-5846942-A | Cholecystokinin antagonists, their preparation and therapeutic use | WARNER-LAMBERT COMPANY (US) | 1998-12-08 | — | — | US | disclosed |
| US-5593967-A | Cholecystokinin antagonists, their preparation and therapeutic use | WARNER-LAMBERT COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0547178-A4 | NOVEL CHOLECYSTOKININ ANTAGONISTS, THEIR PREPARATION AND THERAPEUTIC USE | WARNER LAMBERT CO (US) | 1994-07-06 | — | — | EP | disclosed |
| US-5254589-A | Anticholesterol agent | WARNER-LAMBERT COMPANY (US) | 1993-10-19 | — | — | US | disclosed |
| EP-0547178-A1 | NOVEL CHOLECYSTOKININ ANTAGONISTS, THEIR PREPARATION AND THERAPEUTIC USE | WARNER-LAMBERT COMPANY (US) | 1993-06-23 | — | — | EP | disclosed |
| WO-1993008161-A1 | SULFONYL UREA AND CARBAMATE ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-04-29 | — | — | WO | disclosed |
| WO-1992004045-A1 | NOVEL CHOLECYSTOKININ ANTAGONISTS, THEIR PREPARATION AND THERAPEUTIC USE | WARNER-LAMBERT COMPANY (US) | 1992-03-19 | — | — | WO | disclosed |
| US-5087726-A | Carbamate ACAT inhibitors | WARNER-LAMBERT COMPANY (US) | 1992-02-11 | — | — | US | disclosed |
| US-4751173-A | USING QUATERNARY COMPOUND; RAPID, SELECTIVE | FUJI PHOTO FILM CO., LTD. (JP) | 1988-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295866-A1 | Synthesis And Use Of Glycoside Pro-Drug Analogs | GCG, CYP3A5, UGT1A6 | SCN5A 1423/4885SCN9A 3539/4885SCN10A 2714/4885 |
| US-20100087536-A1 | AMINO ACID DERIVED PRODRUGS OF PROPOFOL, COMPOSITIONS, USES AND CRYSTALLINE FORMS THEREOF | PELP1, CYP3A5, CYP2C19 | SCN5A 254/4885SCN9A 677/4885SCN10A 634/4885 |
| US-20120264702-A1 | Synthesis And Use Of Glycoside Derivatives of Propofol | CYP3A5, CYP3A4, UGT1A4 | SCN5A 529/4885SCN9A 2695/4885SCN10A 1554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.