Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1354232 | 0.82 | SYK (1.00) | SYK | |
| SCHEMBL1354237 | 0.82 | SYK (1.00) | SYK | |
| SCHEMBL1353407 | 0.82 | SYK (1.00) | SYK | |
| SCHEMBL1353410 | 0.82 | SYK (1.00) | SYK | |
| SCHEMBL1355350 | 0.80 | SYK (0.88) | SYK | |
| SCHEMBL1355347 | 0.80 | SYK (0.88) | SYK | |
| SCHEMBL1355029 | 0.80 | SYK (0.86) | SYK | |
| SCHEMBL14052064 | 0.80 | SYK (0.69) | SYK | |
| SCHEMBL1355024 | 0.80 | SYK (0.86) | SYK | |
| SCHEMBL1354345 | 0.79 | SYK (1.00) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136995-A2 | INHIBITORS OF SYK PROTEIN KINASE | PORTOLA PHARMACEUTICALS, INC. (US) | 2009-11-12 | — | — | WO | disclosed |