Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 10/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NAAA | Q02083 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10811922 | 0.92 | EPHX1 (0.68) | EPHX1SMN1; SMN2GAAMAPK1HTT | |
| SCHEMBL1690687 | 0.92 | EPHX1 (0.68) | EPHX1SMN1; SMN2GAAMAPK1HTT | |
| SCHEMBL28059725 | 0.92 | EPHX1 (0.68) | EPHX1SMN1; SMN2GAAMAPK1HTT | |
| SCHEMBL21059112 | 0.90 | EPHX1 (0.69) | EPHX1SMN1; SMN2GAAMAPK1HTT | |
| SCHEMBL24905881 | 0.89 | EPHX1 (0.69) | EPHX1SMN1; SMN2NAAANPC1RAB9A | |
| SCHEMBL16699820 | 0.89 | EPHX1 (0.69) | EPHX1SMN1; SMN2NAAANPC1RAB9A | |
| SCHEMBL12195994 | 0.88 | EPHX1 (1.00) | EPHX1NAAAASAH1 | |
| SCHEMBL14424446 | 0.87 | EPHX1 (0.67) | EPHX1SMN1; SMN2GAAMAPK1HTT | |
| SCHEMBL2801497 | 0.87 | EPHX1 (0.67) | EPHX1SMN1; SMN2GAAMAPK1HTT | |
| SCHEMBL5597213 | 0.87 | EPHX1 (0.67) | EPHX1SMN1; SMN2GAANAAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622526-B2 | Thermoset material based on antiplasticizing polythiourethane and ophthalmic lens comprising an antiplasticized thermoset material | ESSILOR INTERNATIONAL (FR) | 2009-11-24 | — | — | US | disclosed |
| US-7622526-B2 | Thermoset material based on antiplasticizing polythiourethane and ophthalmic lens comprising an antiplasticized thermoset material | ESSILOR INTERNATIONAL (FR) | 2009-11-24 | — | — | US | disclosed |