Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 16/20 | 0.71 |
| ▸ | CDC7 | O00311 | 3/20 | 0.71 |
| ▸ | CDK2 | P24941 | 3/20 | 0.71 |
| ▸ | CSNK1A1 | P48729 | 3/20 | 0.71 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.71 |
| ▸ | CDK9 | P50750 | 3/20 | 0.71 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.71 |
| ▸ | GSK3B | P49841 | 3/20 | 0.71 |
| ▸ | PLK4 | O00444 | 2/20 | 0.71 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.71 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.71 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.71 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.71 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.71 |
| ▸ | PRKCG | P05129 | 2/20 | 0.71 |
| ▸ | CDK1 | P06493 | 2/20 | 0.71 |
| ▸ | PRKACA | P17612 | 2/20 | 0.71 |
| ▸ | MARK3 | P27448 | 2/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.71 |
| ▸ | FRK | P42685 | 2/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1134007 | 0.84 | JAK2 (0.65) | JAK2CDC7CDK2CSNK1A1CSNK1D | |
| SCHEMBL1207892 | 0.83 | JAK2 (0.84) | JAK2CDC7CDK2CSNK1A1CSNK1D | |
| SCHEMBL1133999 | 0.83 | JAK2 (1.00) | JAK2CDC7CDK2CSNK1A1CSNK1D | |
| SCHEMBL13977717 | 0.83 | JAK2 (0.72) | JAK2CDC7CDK2CSNK1A1CSNK1D | |
| SCHEMBL15300558 | 0.81 | JAK2 (0.72) | JAK2CDC7CDK2CSNK1A1CSNK1D | |
| SCHEMBL1759878 | 0.80 | MAPT (0.72) | JAK2CDC7CDK2CSNK1A1CSNK1D | |
| SCHEMBL4181635 | 0.78 | JAK2 (0.73) | JAK2CDC7CDK2CSNK1A1CSNK1D | |
| SCHEMBL13732436 | 0.74 | JAK2 (1.00) | JAK2CDC7CDK2CSNK1A1CSNK1D | |
| SCHEMBL1208304 | 0.73 | JAK2 (0.82) | JAK2CDC7CDK2CSNK1A1CSNK1D | |
| SCHEMBL4191117 | 0.73 | JAK2 (0.69) | JAK2CDC7CDK2CSNK1A1CSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133170-A1 | PROCESS FOR THE PREPARATION OF 5-(2-AMINO-PYRIMIDIN-4-YL)-2-ARYL-1H-PYRROLE-3-CARBOXAMIDES | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2009-11-05 | — | — | WO | disclosed |