Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15598261 | 0.85 | — | — | |
| SCHEMBL14619322 | 0.79 | ADORA2A (0.34) | — | |
| SCHEMBL20998863 | 0.79 | CDC7 (0.30) | — | |
| SCHEMBL18519865 | 0.79 | ADORA2A (0.31) | — | |
| SCHEMBL14311050 | 0.79 | LIMK1 (0.33) | LIMK1L3MBTL1 | |
| SCHEMBL18520049 | 0.77 | — | — | |
| SCHEMBL18519951 | 0.77 | ADORA2A (0.34) | — | |
| SCHEMBL18526551 | 0.74 | ADORA2A (0.34) | — | |
| SCHEMBL19655643 | 0.74 | ADORA2A (0.37) | — | |
| SCHEMBL19978863 | 0.73 | PDPK1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022083686-A1 | MODIFIED NUCLEOSIDE OR NUCLEOTIDE | 深圳华大生命科学研究院 | 2022-04-28 | — | — | WO | disclosed |
| US-9701707-B2 | Methods of synthesizing substituted purine compounds | Epizyme, Inc. (US) | 2017-07-11 | — | — | US | disclosed |
| US-9688714-B2 | Substituted purine compounds | Epizyme, Inc. (US) | 2017-06-27 | — | — | US | disclosed |
| WO-2017027645-A1 | CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2017-02-16 | — | — | WO | disclosed |
| EP-2135948-B1 | ENA nucleic acid drugs modifying splicing in mRNA precursor | MATSUO MASAFUMI (JP) | 2014-09-17 | — | — | EP | disclosed |
| US-7612187-B2 | 2-azapurine compounds and their uses | ROCHE DIAGNOSTICS, GMBH (DE) | 2009-11-03 | — | — | US | disclosed |
| WO-2007020018-A1 | USE OF PURINERGIC AND PYRIMIDINERGIC RECEPTOR AGONISTS FOR DENDRITIC CELLS BASED IMMUNOTHERAPIES | UNIVERSITE LIBRE DE BRUXELLES (BE) | 2007-02-22 | — | — | WO | disclosed |