Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL822576 | 0.90 | HPGD (0.55) | KDM4EMEN1KMT2AMAPTHPGD | |
| SCHEMBL16692184 | 0.87 | KDM4E (0.50) | KDM4EMEN1KMT2AMAPTHPGD | |
| SCHEMBL762312 | 0.87 | KDM4E (0.50) | KDM4EMEN1KMT2AMAPTHPGD | |
| SCHEMBL16692125 | 0.84 | KDM4E (0.48) | KDM4EMEN1KMT2AMAPTHPGD | |
| SCHEMBL16692180 | 0.84 | KDM4E (0.48) | KDM4EMEN1KMT2AMAPTHPGD | |
| SCHEMBL15763114 | 0.84 | KDM4E (0.55) | KDM4EMEN1KMT2AMAPTHPGD | |
| SCHEMBL762055 | 0.84 | KMT2A (0.50) | KDM4EMEN1KMT2AMAPTHPGD | |
| SCHEMBL762117 | 0.83 | KDM4E (0.50) | KDM4EMEN1KMT2AMAPTHPGD | |
| SCHEMBL763127 | 0.83 | KDM4E (0.60) | KDM4EMEN1KMT2AMAPTHPGD | |
| SCHEMBL763102 | 0.83 | KDM4E (0.47) | KDM4EMEN1KMT2AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009141236-A1 | SPIROPYRANS HAVING FLUOROPHORIC GROUPS | BASF SE (DE) | 2009-11-26 | — | — | WO | disclosed |