Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4579266 | 0.90 | — | — | |
| SCHEMBL20734558 | 0.86 | HIF1A (0.60) | HIF1ATSHRCA3CA5ACA5B | |
| SCHEMBL13625477 | 0.80 | HIF1A (0.53) | HIF1ATSHRCA3CA5ACA5B | |
| SCHEMBL26741099 | 0.80 | TSHR (0.42) | HIF1ATSHRFAAHTRPV1ALDH1A1 | |
| SCHEMBL28059543 | 0.80 | HIF1A (0.60) | HIF1ATSHRFAAHTRPV1ALDH1A1 | |
| SCHEMBL58606 | 0.80 | — | — | |
| SCHEMBL48646 | 0.80 | — | — | |
| SCHEMBL16859762 | 0.77 | — | — | |
| SCHEMBL2677189 | 0.77 | — | — | |
| SCHEMBL196890 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013142298-A1 | STABLE PEPTIDE MIMETICS OF THE HIV-1 GP41 PRE-HAIRPIN INTERMEDIATE | MERCK SHARP & DOHME CORP. (US) | 2013-09-26 | — | — | WO | disclosed |
| WO-2009136352-A1 | ANTI-ANGIOGENIC COMPOUNDS | COVX TECHNOLOGIES IRELAND, LTD. (IE) | 2009-11-12 | — | — | WO | disclosed |