Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2193746 | 0.87 | BRAF (0.59) | BRAFEIF2AK3 | |
| SCHEMBL13625133 | 0.85 | BRAF (0.70) | BRAFEIF2AK3 | |
| SCHEMBL13625131 | 0.85 | BRAF (0.53) | BRAFEIF2AK3 | |
| SCHEMBL15615377 | 0.84 | BRAF (0.56) | BRAFEIF2AK3 | |
| SCHEMBL9988665 | 0.81 | BRAF (0.64) | BRAFEIF2AK3 | |
| SCHEMBL2191325 | 0.81 | BRAF (0.60) | BRAFEIF2AK3 | |
| SCHEMBL2194851 | 0.80 | BRAF (0.56) | BRAFEIF2AK3 | |
| SCHEMBL1726925 | 0.80 | BRAF (0.65) | BRAFEIF2AK3 | |
| SCHEMBL2192785 | 0.80 | BRAF (0.81) | BRAF | |
| SCHEMBL1726308 | 0.79 | BRAF (0.76) | BRAFEIF2AK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009137391-A2 | BENZENE SULFONAMIDE THIAZOLE AND OXAZOLE COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-11-12 | — | — | WO | disclosed |