Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PYGL | P06737 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22403771 | 0.85 | HPGD (0.54) | POLBHPGDMEN1KMT2A | |
| SCHEMBL15109535 | 0.83 | HPGD (0.49) | POLBHDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL13806431 | 0.83 | POLB (0.51) | POLBHDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL19647049 | 0.80 | GAA (0.54) | POLBHDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL16425208 | 0.79 | POLB (0.51) | POLBHPGDMEN1RAB9AKMT2A | |
| SCHEMBL14147680 | 0.79 | GAA (0.49) | POLBHDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL15075046 | 0.77 | POLB (0.56) | POLBHPGDMEN1KMT2ALMNA | |
| SCHEMBL6413637 | 0.76 | CA1 (0.55) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL13625979 | 0.76 | HPGD (0.46) | POLBHDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL15109630 | 0.75 | KDM4E (0.74) | POLBHPGDMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013105013-A1 | MUTANT ANTIBODIES AND CONJUGATION THEREOF | COVX TECHNOLOGIES IRELAND LIMITED (IE) | 2013-07-18 | — | — | WO | disclosed |
| WO-2009136352-A1 | ANTI-ANGIOGENIC COMPOUNDS | COVX TECHNOLOGIES IRELAND, LTD. (IE) | 2009-11-12 | — | — | WO | disclosed |