Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL735226 | 0.92 | AURKA (1.00) | AURKAAURKB | |
| SCHEMBL758931 | 0.90 | AURKA (0.85) | AURKAAURKB | |
| SCHEMBL758933 | 0.90 | AURKA (0.85) | AURKAAURKB | |
| SCHEMBL756650 | 0.90 | AURKA (0.85) | AURKAAURKB | |
| SCHEMBL759799 | 0.90 | AURKA (0.85) | AURKAAURKB | |
| SCHEMBL764021 | 0.90 | AURKA (0.85) | AURKAAURKB | |
| SCHEMBL757690 | 0.90 | AURKA (0.85) | AURKAAURKB | |
| SCHEMBL759086 | 0.90 | AURKA (0.84) | AURKAAURKB | |
| SCHEMBL757348 | 0.90 | AURKA (0.81) | AURKAAURKB | |
| SCHEMBL756659 | 0.89 | AURKA (0.84) | AURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009134658-A2 | FUSED BICYCLIC PYRIMIDINE COMPOUNDS AS AURORA KINASE INHIBITORS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2009-11-05 | — | — | WO | disclosed |