Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 5/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11995852 | 0.89 | EPHX1 (0.48) | CCR3MCHR1EPHX1RAB9AMEN1 | |
| SCHEMBL1411686 | 0.89 | EPHX1 (0.48) | CCR3MCHR1EPHX1RAB9AMEN1 | |
| SCHEMBL8989797 | 0.89 | CCR3 (0.43) | CCR3MCHR1EPHX1KDM4ERAB9A | |
| SCHEMBL2392413 | 0.88 | EPHX1 (0.53) | CCR3MCHR1EPHX1RAB9AHTR3A | |
| SCHEMBL13619983 | 0.88 | CCR3 (0.43) | CCR3MCHR1EPHX1KDM4ERAB9A | |
| SCHEMBL13620001 | 0.88 | KMT2A (0.40) | CCR3MCHR1EPHX1KDM4EMEN1 | |
| SCHEMBL2391511 | 0.88 | EPHX1 (0.55) | MCHR1EPHX1RAB9AKMT2AALDH1A1 | |
| SCHEMBL8988043 | 0.87 | MAPT (0.43) | CCR3MCHR1EPHX1KDM4EMEN1 | |
| SCHEMBL1411818 | 0.87 | MAPT (0.41) | CCR3MCHR1KDM4EMEN1POLB | |
| SCHEMBL1411780 | 0.84 | KDM1A (0.41) | MCHR1EPHX1KDM4EPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009137681-A1 | THERAPEUTICALLY USEFUL SUBSTITUTED HYDROPYRIDO [3,2,1-IJ] QUINOLINE COMPOUNDS | ALLERGAN, INC. (US) | 2009-11-12 | — | — | WO | disclosed |