Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.52 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1888964 | 0.84 | PPARG (0.64) | PPARGAGTR1ACHE | |
| SCHEMBL14136135 | 0.83 | PPARG (0.51) | PPARGAGTR1ACHEAGTR2 | |
| SCHEMBL1893927 | 0.82 | PPARG (0.55) | PPARGAGTR1ACHEAGTR2 | |
| SCHEMBL1892450 | 0.82 | PPARG (0.49) | PPARGAGTR1ACHEAGTR2 | |
| SCHEMBL1890122 | 0.81 | PPARG (0.61) | PPARGAGTR1ACHE | |
| SCHEMBL1893340 | 0.81 | PPARG (0.51) | PPARGAGTR1ACHE | |
| SCHEMBL1897246 | 0.80 | PPARG (0.47) | PPARGAGTR1ACHE | |
| SCHEMBL1889717 | 0.79 | PPARG (0.56) | PPARGAGTR1ACHE | |
| SCHEMBL1894333 | 0.79 | PPARG (0.55) | PPARGAGTR1ACHE | |
| SCHEMBL1886369 | 0.78 | PPARG (0.64) | PPARGAGTR1ACHEAGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133970-A1 | CRYSTALLINE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-05 | — | — | WO | disclosed |