Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1203837 | 0.89 | BTK (0.51) | BTK | |
| SCHEMBL1205490 | 0.89 | BTK (0.51) | BTK | |
| SCHEMBL1204149 | 0.89 | BTK (0.51) | BTK | |
| SCHEMBL161076 | 0.83 | BTK (0.49) | BTK | |
| SCHEMBL19545087 | 0.83 | BTK (0.49) | BTK | |
| SCHEMBL1204826 | 0.82 | BTK (0.42) | BTK | |
| SCHEMBL160223 | 0.79 | BTK (0.46) | BTK | |
| SCHEMBL10256464 | 0.77 | BTK (0.46) | BTK | |
| SCHEMBL10256242 | 0.77 | BTK (0.39) | BTK | |
| SCHEMBL12177877 | 0.75 | BTK (0.36) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009137596-A1 | SUBSTITUTED AMIDES, METHOD OF MAKING, AND USE AS BTK INHIBITORS | CGI PHARMACEUTICALS, INC. (US) | 2009-11-12 | — | — | WO | disclosed |
| WO-2009039397-A2 | SUBSTITUTED AMIDES, METHODS OF MAKING, USE THEREOF FOR THE TREATMENT OF DISEASES SUCH AS CANCER | CGI PHARMACEUTICALS, INC. (US) | 2009-03-26 | — | — | WO | disclosed |