Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5539493 | 0.88 | F10 (0.48) | F10 | |
| SCHEMBL4606938 | 0.84 | F10 (0.68) | F10 | |
| SCHEMBL4604418 | 0.83 | F10 (0.78) | F10 | |
| SCHEMBL4606847 | 0.83 | F10 (0.78) | F10 | |
| SCHEMBL3830242 | 0.83 | F10 (0.70) | F10 | |
| SCHEMBL1030080 | 0.80 | F10 (0.53) | F10 | |
| SCHEMBL4605676 | 0.80 | F10 (0.76) | F10 | |
| SCHEMBL13626551 | 0.79 | F10 (0.55) | F10 | |
| SCHEMBL4598108 | 0.79 | F10 (0.69) | F10 | |
| SCHEMBL4598973 | 0.79 | F10 (0.69) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612089-B2 | Tetrahydroisoquinolines as factor Xa inhibitors | PORTOLA PHARMACEUTICALS, INC. (US) | 2009-11-03 | — | — | US | disclosed |
| US-7612089-B2 | Tetrahydroisoquinolines as factor Xa inhibitors | PORTOLA PHARMACEUTICALS, INC. (US) | 2009-11-03 | — | — | US | disclosed |