SCHEMBL13626529

SCHEMBL13626529

Cc1cccc(Oc2ccc(-c3nc(C4CCC4)n4ccnc(N)c34)cc2)c1F

nearest known ligand 0.85

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TNK2 Q07912 20/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4368092 0.92 TNK2 (1.00) TNK2
SCHEMBL4354388 0.91 TNK2 (1.00) TNK2
SCHEMBL4369106 0.88 TNK2 (1.00) TNK2
SCHEMBL4357566 0.87 TNK2 (1.00) TNK2
SCHEMBL25981044 0.86 TNK2 (0.64) TNK2
SCHEMBL1129341 0.86 TNK2 (1.00) TNK2
SCHEMBL4357705 0.85 TNK2 (1.00) TNK2
SCHEMBL1129377 0.85 TNK2 (1.00) TNK2
SCHEMBL4354046 0.84 TNK2 (1.00) TNK2
SCHEMBL4364449 0.84 TNK2 (1.00) TNK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009143051-A1 SUBSTITUTED IMIDAZOPYR-AND IMIDAZOTRI-AZINES OSI PHARMACEUTICALS, INC. (US) 2009-11-26 WO disclosed