Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9963213 | 0.93 | CNR2 (0.49) | CNR2HCRTR1HCRTR2EPHX2GPR119 | |
| SCHEMBL6975824 | 0.85 | CNR2 (0.47) | CNR2HCRTR1HCRTR2EPHX2GPR119 | |
| SCHEMBL10094568 | 0.85 | CNR2 (0.47) | CNR2HCRTR1HCRTR2EPHX2GPR119 | |
| SCHEMBL10094552 | 0.84 | NPC1 (0.47) | CNR2HCRTR1HCRTR2EPHX2GPR119 | |
| SCHEMBL15931980 | 0.82 | CNR2 (0.45) | CNR2HCRTR1HCRTR2EPHX2GPR119 | |
| SCHEMBL27875026 | 0.81 | CNR2 (0.43) | CNR2HCRTR1HCRTR2EPHX2GPR119 | |
| SCHEMBL27875027 | 0.81 | CNR2 (0.45) | CNR2HCRTR1HCRTR2EPHX2GPR119 | |
| SCHEMBL20969916 | 0.81 | CNR2 (0.45) | CNR2HCRTR1HCRTR2EPHX2GPR119 | |
| SCHEMBL1673933 | 0.81 | NR1H4 (0.47) | CNR2HCRTR1HCRTR2EPHX2GPR119 | |
| SCHEMBL1128456 | 0.80 | CNR2 (0.42) | CNR2HCRTR1HCRTR2EPHX2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009141238-A1 | GPR119 RECEPTOR AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-11-26 | — | — | WO | disclosed |