SCHEMBL1362670

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1364644	0.96	PDE4B (0.50)	PDE4BMAPK1
	SCHEMBL1362711	0.93	PDE4B (0.43)	PDE4BWDR5
	SCHEMBL1364188	0.93	PDE4B (0.48)	PDE4BMAPK1NR3C1
	SCHEMBL4098533	0.92	PDE4B (0.50)	PDE4BMAPK1NR3C1
	SCHEMBL7999898	0.92	PDE4B (0.49)	PDE4BMAPK1
	SCHEMBL3425812	0.91	PDE4B (0.48)	PDE4BMAPK1
	SCHEMBL3424657	0.91	PDE4B (0.48)	PDE4BMAPK1
	SCHEMBL13761217	0.91	PDE4B (0.53)	PDE4BMAPK1NR3C1WDR5
	SCHEMBL13750936	0.90	PDE4B (0.47)	PDE4BMAPK1
	SCHEMBL1363353	0.89	PDE4B (0.46)	PDE4BMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.