Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 18/20 | 0.57 |
| ▸ | KDM1A | O60341 | 15/20 | 0.57 |
| ▸ | RCOR1 | Q9UKL0 | 15/20 | 0.57 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.54 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.54 |
| ▸ | KMT5A | Q9NQR1 | 1/20 | 0.54 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.52 |
| ▸ | SPIN1 | Q9Y657 | 2/20 | 0.50 |
| ▸ | WHR1 | P49842 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1428037 | 0.90 | EHMT2 (0.70) | EHMT2KDM1ARCOR1EZH2PRMT1 | |
| SCHEMBL9911829 | 0.89 | EHMT2 (0.58) | EHMT2KDM1ARCOR1EZH2PRMT1 | |
| SCHEMBL1428110 | 0.89 | EHMT2 (0.71) | EHMT2KDM1ARCOR1EZH2PRMT1 | |
| SCHEMBL1427837 | 0.88 | EHMT2 (0.64) | EHMT2KDM1ARCOR1EZH2PRMT1 | |
| SCHEMBL9911812 | 0.88 | EHMT2 (0.63) | EHMT2KDM1ARCOR1EZH2PRMT1 | |
| SCHEMBL9911828 | 0.87 | EHMT2 (0.57) | EHMT2KDM1ARCOR1EZH2PRMT1 | |
| SCHEMBL13627118 | 0.87 | EHMT2 (0.57) | EHMT2KDM1ARCOR1EZH2PRMT1 | |
| SCHEMBL1428514 | 0.87 | EHMT2 (0.67) | EHMT2KDM1ARCOR1EZH2PRMT1 | |
| SCHEMBL1428164 | 0.87 | EHMT2 (0.66) | EHMT2KDM1ARCOR1EZH2PRMT1 | |
| SCHEMBL9911833 | 0.87 | EHMT2 (0.57) | EHMT2KDM1ARCOR1EZH2PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143058-A1 | BICYCLIC COMPOUNDS HAVING ACTIVITY AT THE CXCR4 RECEPTOR | ALLERGAN, INC. (US) | 2009-11-26 | — | — | WO | disclosed |