Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 19/20 | 0.64 |
| ▸ | KDM1A | O60341 | 17/20 | 0.64 |
| ▸ | RCOR1 | Q9UKL0 | 17/20 | 0.64 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.54 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.54 |
| ▸ | KMT5A | Q9NQR1 | 1/20 | 0.54 |
| ▸ | WHR1 | P49842 | 1/20 | 0.53 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1427588 | 0.92 | EHMT2 (0.68) | EHMT2KDM1ARCOR1EZH2PRMT1 | |
| SCHEMBL9911758 | 0.90 | EHMT2 (0.72) | EHMT2KDM1ARCOR1EZH2PRMT1 | |
| SCHEMBL1427844 | 0.88 | EHMT2 (0.76) | EHMT2KDM1ARCOR1EZH2PRMT1 | |
| SCHEMBL9911817 | 0.86 | EHMT2 (0.66) | EHMT2KDM1ARCOR1EZH2PRMT1 | |
| SCHEMBL1428491 | 0.85 | EHMT2 (0.79) | EHMT2KDM1ARCOR1EZH2PRMT1 | |
| SCHEMBL9911793 | 0.84 | EHMT2 (0.70) | EHMT2KDM1ARCOR1EZH2PRMT1 | |
| SCHEMBL1430691 | 0.84 | EHMT2 (0.69) | EHMT2KDM1ARCOR1EZH2PRMT1 | |
| SCHEMBL9911842 | 0.82 | EHMT2 (0.76) | EHMT2KDM1ARCOR1EZH2PRMT1 | |
| SCHEMBL1428037 | 0.82 | EHMT2 (0.70) | EHMT2KDM1ARCOR1EZH2PRMT1 | |
| SCHEMBL9911824 | 0.81 | EHMT2 (0.69) | EHMT2KDM1ARCOR1EZH2PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143058-A1 | BICYCLIC COMPOUNDS HAVING ACTIVITY AT THE CXCR4 RECEPTOR | ALLERGAN, INC. (US) | 2009-11-26 | — | — | WO | disclosed |