Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 19/20 | 0.98 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.62 |
| ▸ | PTAFR | P25105 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13451440 | 1.00 | TACR1 (0.98) | TACR1CYP3A4SIGMAR1PTAFR | |
| SCHEMBL13627549 | 1.00 | TACR1 (0.98) | TACR1CYP3A4SIGMAR1PTAFR | |
| SCHEMBL13627583 | 1.00 | TACR1 (0.98) | TACR1CYP3A4SIGMAR1PTAFR | |
| SCHEMBL5499061 | 1.00 | TACR1 (0.98) | TACR1CYP3A4SIGMAR1PTAFR | |
| SCHEMBL13627577 | 1.00 | TACR1 (0.98) | TACR1CYP3A4SIGMAR1PTAFR | |
| SCHEMBL13627548 | 1.00 | TACR1 (0.98) | TACR1CYP3A4SIGMAR1PTAFR | |
| SCHEMBL13627584 | 1.00 | TACR1 (0.98) | TACR1CYP3A4SIGMAR1PTAFR | |
| Hydrochloric Acid SCHEMBL5495955 | 0.99 | TACR1 (0.97) | TACR1CYP3A4SIGMAR1PTAFR | |
| SCHEMBL13627550 | 0.99 | TACR1 (1.00) | TACR1CYP3A4SIGMAR1PTAFR | |
| SCHEMBL13451567 | 0.99 | TACR1 (1.00) | TACR1CYP3A4SIGMAR1PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7619092-B2 | Piperidine compounds | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-11-17 | — | — | US | disclosed |
| US-7619092-B2 | Piperidine compounds | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-11-17 | — | — | US | disclosed |