Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 19/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.71 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.71 |
| ▸ | PTAFR | P25105 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13627752 | 1.00 | TACR1 (0.77) | TACR1CYP3A4SIGMAR1PTAFR | |
| SCHEMBL13627754 | 0.92 | TACR1 (0.79) | TACR1CYP3A4SIGMAR1PTAFR | |
| SCHEMBL13627862 | 0.91 | TACR1 (0.78) | TACR1CYP3A4SIGMAR1PTAFR | |
| SCHEMBL13451710 | 0.88 | TACR1 (0.73) | TACR1CYP3A4SIGMAR1PTAFR | |
| SCHEMBL13451630 | 0.88 | TACR1 (0.73) | TACR1CYP3A4SIGMAR1PTAFR | |
| SCHEMBL13627755 | 0.88 | TACR1 (0.73) | TACR1CYP3A4SIGMAR1PTAFR | |
| SCHEMBL13627535 | 0.87 | TACR1 (0.83) | TACR1CYP3A4SIGMAR1PTAFR | |
| SCHEMBL13451392 | 0.87 | TACR1 (0.83) | TACR1CYP3A4SIGMAR1PTAFR | |
| SCHEMBL13627532 | 0.87 | TACR1 (0.83) | TACR1CYP3A4SIGMAR1PTAFR | |
| Hydrochloric Acid SCHEMBL6600739 | 0.86 | TACR1 (0.98) | TACR1CYP3A4SIGMAR1PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7619092-B2 | Piperidine compounds | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-11-17 | — | — | US | disclosed |
| US-7619092-B2 | Piperidine compounds | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-11-17 | — | — | US | disclosed |