Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 18/20 | 0.64 |
| ▸ | PTGDR | Q13258 | 10/20 | 0.60 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.55 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.55 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.55 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.55 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.55 |
| ▸ | PTGFR | P43088 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5777316 | 0.78 | TBXA2R (1.00) | TBXA2RPTGDRPTGDR2 | |
| SCHEMBL5778629 | 0.77 | TBXA2R (0.76) | TBXA2RPTGDRPTGDR2 | |
| SCHEMBL5835535 | 0.76 | TBXA2R (0.77) | TBXA2RPTGDRPTGER1PTGER3PTGER2 | |
| SCHEMBL5835872 | 0.76 | TBXA2R (0.84) | TBXA2RPTGDRPTGDR2 | |
| SCHEMBL5776865 | 0.75 | TBXA2R (0.59) | TBXA2RPTGDRPTGDR2 | |
| SCHEMBL5777305 | 0.74 | TBXA2R (1.00) | TBXA2RPTGDRPTGDR2 | |
| SCHEMBL5778917 | 0.73 | TBXA2R (0.74) | TBXA2RPTGDRPTGDR2 | |
| SCHEMBL13416145 | 0.73 | TBXA2R (0.90) | TBXA2RPTGDRPTGDR2 | |
| SCHEMBL5775353 | 0.72 | TBXA2R (1.00) | TBXA2RPTGDRPTGDR2 | |
| SCHEMBL5779067 | 0.72 | TBXA2R (0.69) | TBXA2RPTGDRPTGER1PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7618979-B2 | Pyridopyrrolizine and pyridoindolizine derivatives | MERCK FROSST CANADA LTD. (CA) | 2009-11-17 | — | — | US | disclosed |