Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 7/20 | 0.42 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.42 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.42 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | WNT3 | P56703 | 1/20 | 0.38 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7950882 | 0.85 | NAMPT (0.51) | NAMPTTPSAB1TPSD1TPSG1TGM2 | |
| SCHEMBL7950888 | 0.85 | NAMPT (0.51) | NAMPTTPSAB1TPSD1TPSG1TGM2 | |
| SCHEMBL9735842 | 0.84 | NAMPT (0.46) | NAMPTTPSAB1TPSD1TPSG1TGM2 | |
| SCHEMBL9735280 | 0.84 | NAMPT (0.44) | NAMPTTPSAB1TPSD1TPSG1TGM2 | |
| Water SCHEMBL9737444 | 0.83 | MEN1 (0.42) | NAMPTTPSAB1TPSD1TPSG1TGM2 | |
| SCHEMBL9734630 | 0.82 | NAMPT (0.44) | NAMPTTPSAB1TPSD1TPSG1TGM2 | |
| SCHEMBL9736271 | 0.82 | NAMPT (0.46) | NAMPTTPSAB1TPSD1TPSG1TGM2 | |
| SCHEMBL9734368 | 0.82 | NAMPT (0.46) | NAMPTTPSAB1TPSD1TPSG1TGM2 | |
| SCHEMBL5971671 | 0.82 | NAMPT (0.46) | NAMPTTPSAB1TPSD1TPSG1TGM2 | |
| SCHEMBL13779906 | 0.81 | NAMPT (0.49) | NAMPTTPSAB1TPSD1TPSG1TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622487-B2 | Piperidine derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-24 | — | — | US | disclosed |
| US-7622487-B2 | Piperidine derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-24 | — | — | US | disclosed |