Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | CDC7 | O00311 | 19/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4346525 | 0.83 | CDC7 (0.61) | BRD4CDC7 | |
| SCHEMBL2196043 | 0.83 | CDC7 (0.61) | BRD4CDC7CCNA2CDK2CCNA1 | |
| SCHEMBL4339819 | 0.83 | CDC7 (0.61) | BRD4CDC7CCNA2CDK2CCNA1 | |
| SCHEMBL4351518 | 0.83 | MAPK14 (0.48) | BRD4CDC7CCNA2CDK2CCNA1 | |
| SCHEMBL12423845 | 0.83 | BRD4 (0.64) | BRD4CDC7CCNA2CDK2CCNA1 | |
| SCHEMBL4351487 | 0.83 | BRD4 (0.68) | BRD4CDC7CCNA2CDK2CCNA1 | |
| SCHEMBL12509721 | 0.81 | BRD4 (0.45) | BRD4CDC7CCNA2CDK2CCNA1 | |
| SCHEMBL4344966 | 0.80 | CDC7 (0.64) | BRD4CDC7 | |
| SCHEMBL12509725 | 0.80 | BRD4 (0.44) | BRD4CDC7CCNA2CDK2CCNA1 | |
| SCHEMBL4346399 | 0.80 | CDC7 (0.50) | BRD4CDC7CCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2116530-A1 | NOVEL PYRROLE DERIVATIVE HAVING UREIDE GROUP AND AMINOCARBONYL GROUP AS SUBSTITUENTS | Santen Pharmaceutical Co., Ltd (JP) | 2009-11-11 | — | — | EP | disclosed |